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autoimmunity 
Fri Oct 02, 2009 at 01:52:11 AM EDT
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OK, carry on with the science. As I said in part 1, our immune system is a result of evolution. The primary evolutionary need is/was to defend against invasion by infectious disease agents or pathogens, but the same basic immune response is used when other antigens, including vaccines and self-antigens, are detected. To protect the host effectively, the immune system has to do 4 things:
- pathogen recognition: the presence of an infection must be detected.
- effector functions: cells of the immune system respond to contain the infection and if possible eliminate it completely.
- immune regulation: the immune response must be kept under control so that it does not itself do damage to the body.
- immunological memory: when the initial immune response is over, the immune system stores the 'memory', in order that subsequent encounters will result in stronger, more efficient response.
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There's More...
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Comments, 2476 words in story)
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Sat Sep 26, 2009 at 23:10:39 PM EDT
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At a recent FDA advisory committee meeting to discuss their approach to swine flu vaccines, the GSK representative, guy called Bruce Innis, said:
I think all the manufacturers have presented data that shows that the effects of the adjuvants are limited in time, limited to the space where it is injected and in the draining lymph nodes. They don't have widespread activation of the immune response, and there isn't plausibility that they would activate autoimmunity in organs separate from the muscle where they are injected.
Is he right? There are 2 (non-exclusive) ways to find out. One is to go through the meeting transcripts and see if they did present such data (I did, and they didn't). The other is to take a look at the science.
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There's More...
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Comments, 1763 words in story)
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