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immunology
Tue Jul 21, 2009 at 14:22:11 PM EDT
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You may or may not be aware that MIT offers a LOT of high quality undergrad and grad level courses online and for free (not interactive from what I can tell tho)
I thought these might be of interest.
7.340 Nano-life: An Introduction to Virus Structure and Assembly
Course Highlights
This course features a complete bibliography of readings and sample student assignments in the assignments section.
Course Description
Watson and Crick noted that the size of a viral genome was insufficient to encode a protein large enough to encapsidate it and reasoned, therefore that a virus shell must be composed of multiple, but identical subunits. Today, high resolution structures of virus capsids reveal the basis of this genetic economy as a highly symmetrical structure, much like a geodesic dome composed of protein subunits. Crystallographic structures and cryo-electron microscopy reconstructions combined with molecular data are beginning to reveal how these nano-structures are built. Topics covered in the course will include basic principles of virus structure and symmetry, capsid assembly, strategies for enclosing nucleic acid, proteins involved in entry and exit, and the life cycles of well understood pathogens such as HIV, influenza, polio, and Herpes. A review of cutting edge structural methods is also covered.
site = http://ocw.mit.edu/OcwWeb/Biol...
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There's More...
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Comments, 305 words in story)
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