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taubenberger

cost of sequencing(2)

by: gs

Sun Aug 05, 2007 at 02:35:21 AM EDT

why do we often only get partial sequences or only one segment ,
is it too difficult and expensive or is it secrecy ?

Is the sequencing of old conserved viruses more difficult ?
What does it cost, any estimates ?

I get these from before 1918, only small fragments,
exept for the 1902 chicken with about 9000 nucleotides
out of about 13500.
(the 1909,1911 sequences, are they date-errors ?)

But viruses before 1918 should be particularly interesting,
so why can't we get them ? What would it cost ?

Code:

AF497556 978 Avian 4 (HA) H7 Italy 1902 Influenza A virus (A/chicken/Brescia/440b/1902(H7))
U20471 66 Avian 4 (HA) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
L37795 1027 Avian 7 (MP) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
L37798 890 Avian 8 (NS) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
CY015058 2341 Avian 1 (PB2) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
CY015057 2233 Avian 3 (PA) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
CY015055 1565 Avian 5 (NP) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
CY015054 1027 Avian 7 (MP) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
CY015056 890 Avian 8 (NS) H7N7 Italy 1902 Influenza A virus (A/chicken/Brescia/1902(H7N7))
EF473519 1091 Human 4 (HA) H3 USA 1909/12/07 Influenza A virus (A/Connecticut/3/2003(H3))
EF473606 1806 Human 4 (HA) China 1909/12/07 Influenza B virus (B/Jiangsu/10/2003)
EF473522 1068 Human 4 (HA) H3 USA 1911/12/07 Influenza A virus (A/District of Columbia/4/2003(H3))
EF473546 1103 Human 4 (HA) H3 USA 1911/12/07 Influenza A virus (A/Missouri/12/2003(H3))
AY220475 151 Avian 5 (NP) USA 1916 Influenza A virus (A/cinnamon teal/Utah/1/1916)
AY095226 166 Avian 4 (HA) H1 USA 1917 Influenza A virus (A/Brant Goose/1/1917(H1N?))
AY095227 288 Avian 4 (HA) H1 USA 1917 Influenza A virus (A/Brant Goose/1/1917(H1N?))
AY095228 151 Avian 5 (NP) H1 USA 1917 Influenza A virus (A/Brant Goose/1/1917(H1N?))